Summary and Info
Interleukin 7 (IL-7) was discovered in 1988 as a factor that promotes the growth of murine В cell precursors. IL-7 is a single-chain protein of 25kDa produced predominantly by epithelial cells, especially keratino-cytes and thymic epithelial cells. It plays an essential, nonredundant role in the development of T and В cells in the mouse and of T cells in humans. IL-7 promotes survival and proliferation of T cell precursors in humans and mice and of В cell precursors in mice. It may also play a role in differentiation of T cells (notably of TCR76 T cells) and В cells. In addition, IL-7 affects survival and proliferation of mature T cells but not of mature В cells. Some data suggest that IL-7 is important for the function of mature T cells in the periphery. There is no evidence that IL-7 is involved in development of cells other than T and В cells, but this cytokine may affect the function of mature NK cells and monocytes/macrophages. Data in the mouse suggest that IL-7 may be of clinical benefit by stimulating T cell development in recipients of hematopoietic stem cell transplantation, but so far no clinical trials have been performed.
More About the Author
Spitshine is the third studio album by Australian hip hop artist and member of The Herd, Urthboy. It was released on 28 August 2009.
Review and Comments
Rate the Book
IL7 0 out of 5 stars based on 0 ratings.