Summary and Info
Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.
More About the Author
John Howland (c. 1591 – February 23, 1672/3) was a passenger on the Mayflower. He was an indentured servant and in later years, the executive assistant and personal secretary to Governor John Carver and accompanied the Separatists and other passengers when they left England to settle in Plymouth, Massachusetts.
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