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Content: Cancer drug discovery and development : new paradigms for a new millennium / E.A. Sausville ... [et al.] -- Evolutionary biosynthesis of anticancer drugs / George R. Pettit -- Some recent developments in the synthesis and structure-activity relationship of novel taxanes / John F. Kadow ... [et al.] -- New generation taxoids and hybrids of microtubule-stabilizing anticancer agents / Iwao Ojima ... [et al.] -- Discodermolide and taxol : a synergistic drug combination in human carcinoma cell lines / Susan Band Horwitz ... [et al.] -- Highly efficient semisynthesis of biologically active epothilone derivatives / Gregory D. Vite ... [et al.] -- Synthetic and semisynthetic analogs of epothilones : chemistry and biological activity / Karl-Heinz Altmann ... [et al.] -- Synthesis and biological activity of epothilones / Ulrich Klar ... [et al.] -- Epothilones and sarcodictyins : from combinatorial libraries to designed analogs / Nicolas Winssinger and K.C. Nicolaou -- Synthesis and structure-activity relationship studies of cryptophycins : a novel class of potent antimitotic antitumor depsipeptides / Chuan Shih ... [et al.] -- Farnesyltransferase inhibitors as potential anticancer agents / J.B. Gibbs ... [et al.] -- Farnesyltransferase inhibitors : from squalene synthase inhibitors to the clinical agent BMS-214662 / John T. Hunt -- Inhibiting farnesyl protein transferase with Sch-66336 : potentially a selective noncytotoxic therapy for human cancer / A.G. Taveras ... [et al.] -- Pyrrolo[2,3-d]pyrimidine and pyrazolo[3,4-d]pyrimidine derivatives as selective inhibitors of the EGF receptor tryosine kinase / G. Caravatti ... [et al.] -- STI571 : a new treatment modality for CML? / Jürg Zimmermann, Pascal Furet, and Elisabeth Buchdunger -- The discovery and development of second-generation matrix metalloproteinase inhibitors for the treatment of cancer / Andy Baxter and John Montana -- Prospects for antiangiogenic therapies based upon VEGF inhibition / Pascal Furet and Paul W. Manley -- Carbohydrate-based tumor antigens as antitumor vaccine agents / Jennifer R. Allen and Samuel J. Danishefsky -- Drugs to enhance the therapeutic potency of anticancer antibodies : antibody-drug conjugates as tumor-activated prodrugs / Walter A. Blättler and Ravi V.J. Chari.
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